Products to Try: Preva® Medicated Wipes

Preva® Wipes (Bayer Animal Health) are an effective antibacterial product safe for use in dogs and cats. The active ingredient is nisin, a natural antimicrobial derived from Lactococcus lactis. It is effective in rapidly killing gram-positive bacteria at very low concentrations. Data has demonstrated low MIC90s for nisin against methicillin- resistant staphylococci we see regularly […] Read more>

In the Pipeline: Therapeutic Monoclonal Antibody Treatment for Pruritus

Biologic medicine uses principles of what we know about normal immune responses to rebalance, restore or stimulate a patient’s own immune system to fight disease. Biotherapeutics used in biologic medicine include immunostimulating cytokines (interferon), colony stimulating factors (erythropoietin) and therapeutic monoclonal antibodies (mAbs). Therapeutic mAbs can be used to block disease relevant proteins (cytokines, receptors) […] Read more>

Feline Herpes Virus: Causes, Symptoms & Treatment

  Feline Herpes Causes and Symptoms Feline Rhinotracheitis typically manifests in cats as an upper respiratory disease, usually accompanied by ocular signs and is caused by a herpes virus (Feline herpes virus-1). However, infection can manifest with skin lesions in the absence of respiratory signs and ocular lesions. Skin lesions usually follow the path of […] Read more>

Apoquel® The NVDS Experience: Where Are We Now?

Apoquel® (oclacitinib, Zoetis), has been a remarkable medication for the reduction of pruritus in dogs that we manage as veterinary dermatologists. We thought it would be helpful to share our clinical experiences.   Apoquel® Uses Use of Apoquel® in the management of canine atopic dermatitis (CAD) has greatly reduced our need for adjunctive systemic glucocorticoids […] Read more>

Diagnosis and Treatment of Pyoderma in Dogs

Deep bacterial pyoderma is a bacterial infection involving the deep layers of the skin; the dermis and sometimes the subcutaneous tissue.  It usually starts as a superficial infection of the hair follicle (folliculitis) that breaks through the follicular wall into the dermis.  The resulting inflammation and infection of the dermis is called furunculosis.  When the […] Read more>

Hypothyroidism in Dogs: Causes, Diagnosis, & Treatment

Causes of Hypothyroidism in Dogs Hypothyroidism, an under production of thyroid hormone, is reported to be the most common hormonal disease in dogs. It may affect any breed as well as mixed breed dogs.  Golden retrievers, Doberman pinschers and Labrador retrievers appear to be at an increased risk of developing the disease.   Typically, one sees […] Read more>

Iatrogenic Hyperadrenocorticism in Dogs (Cushing’s Syndrome)

Hyperadrenocorticism in dogs may occur spontaneously or may be iatrogenic from the administration of glucocorticoids (GC) like prednisone (a steroid). Spontaneous hyperadrenocorticism is pituitary dependent (most commonly a pituitary gland adenoma producing ACTH hormone that signals the adrenal gland to produce cortisol hormone without feedback regulation) or adrenal dependent from an adrenal tumor (tumor produces […] Read more>

Alopecia X in Dogs (Hair Cycle Arrest)

Alopecia X is a name given to a skin condition in the dog resulting in non-inflammatory hair loss. Other names used for the same condition have included adrenal sex hormone imbalance, wooly syndrome, coat funk, black skin disease, pseudo-cushings, and follicular growth dysfunction of plush coated breeds. I now call this alopecic condition hair cycle […] Read more>

Feline Hyperadrenocorticism (Cushing’s Syndrome)

Feline hyperadrenocorticism (HAC) is a rare condition in cats. Spontaneous HAC is associated with increased production of endogenous steroid hormone (cortisol) by the adrenal cortex. 75-80% of cases are pituitary dependent (functional pituitary adenoma) and 25% are caused by an adrenal tumor (carcinoma or microadenoma). Feline HAC may also be iatrogenic from exogenous use of […] Read more>

Treatment for Calcinosis Cutis in Dogs

Calcinosis cutis (CC) is the deposition of inorganic, insoluble mineral salts into the different layers of the skin. It is characterized histologically (under the microscope in tissue samples) by mineralization of dermal collagen fibers, accumulation of macrophages and mixed inflammatory infiltrates, acanthosis (thickening of skin), ulceration and evidence of elimination of mineral through the skin. […] Read more>